Dr. Sebi’s products indicate the recommended dosage on the product label. If the packaging instructs you to take four capsules daily, you can take all four in the morning or break them up throughout the day. Some herbs provide natural energy, so taking them late is not recommended. If the product instructs AM and PM dosages, you will take 4 capsules/tbsps for the entire day. If you still have questions, feel free to call us at 310-838-2490.